Virological and serological aspects of hepatitis B and the delta agent.

The hepatitis B virus (HBV) belongs to a group of viruses termed hepadnaviruses. The 3.2 kb genome encodes for a variety of proteins involved in viral replication (p-gene), transactivation (x-gene), or encodes for structural proteins (c- and s-genes). Several viral and non-viral functions determine the clinical course of HBV infection. The hepatitis D virus resembles a viroid and requires the HBV as a helper virus. The interaction between the viruses is not well understood. More information on the interaction between the human host and viruses is needed to help improve the treatment.